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DNA dC->dU-editing enzyme APOBEC-3G
Ligand
BDBM80399
Substrate
n/a
Meas. Tech.
Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen
Temperature
298.15±n/a K
IC50
1930±97 nM
Comments
extracted
Citation
PubChem, PC Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen PubChem Bioassay (2011)[AID] More Info.:
Target
Name:
DNA dC->dU-editing enzyme APOBEC-3G
Synonyms:
ABC3G_HUMAN | APOBEC3G
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46419.54
Organism:
Homo sapiens (Human)
Description:
gi_13399304
Residue:
384
Sequence:
MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
Inhibitor
Name:
BDBM80399
Synonyms:
2-(4-methyl-4-morpholin-4-iumyl)acetic acid 3-phenylpropyl ester;iodide | 2-(4-methylmorpholin-4-ium-4-yl)acetic acid 3-phenylpropyl ester;iodide | 3-phenylpropyl 2-(4-methylmorpholin-4-ium-4-yl)acetate;iodide | 3-phenylpropyl 2-(4-methylmorpholin-4-ium-4-yl)ethanoate;iodide | MLS000519387 | SMR000129806 | cid_9551070
Type:
Small organic molecule
Emp. Form.:
C16H24NO3
Mol. Mass.:
278.3661
SMILES:
C[N+]1(CC(=O)OCCCc2ccccc2)CCOCC1
Structure:
