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Target
C-C chemokine receptor type 6
Ligand
BDBM78218
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
16600±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM78218
Synonyms:
(E)-4-(3-nitroanilino)-4-oxo-2-butenoic acid ethyl ester | (E)-4-keto-4-(3-nitroanilino)but-2-enoic acid ethyl ester | MLS000389828 | SMR000256102 | cid_2140300 | ethyl (E)-4-(3-nitroanilino)-4-oxobut-2-enoate | ethyl (E)-4-[(3-nitrophenyl)amino]-4-oxidanylidene-but-2-enoate
Type:
Small organic molecule
Emp. Form.:
C12H12N2O5
Mol. Mass.:
264.2341
SMILES:
CCOC(=O)\C=C\C(=O)Nc1cccc(c1)[N+]([O-])=O
Structure:
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