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Target
C-C chemokine receptor type 6
Ligand
BDBM80021
Substrate
n/a
Meas. Tech.
Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50
594±n/a nM
Citation
 PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay (2011)[AID] 
Target
Name:
C-C chemokine receptor type 6
Synonyms:
C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:
Enzyme
Mol. Mass.:
42510.84
Organism:
Homo sapiens (Human)
Description:
P51684
Residue:
374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFGLLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKLLKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISSSTFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKTLVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTVTEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQTSETADNDNASSFTM
  
Inhibitor
Name:
BDBM80021
Synonyms:
(4Z)-2-(3,4-dimethoxyphenyl)-4-[[(4,6-dimethyl-2-pyrimidinyl)hydrazo]methylidene]isoquinoline-1,3-dione | (4Z)-2-(3,4-dimethoxyphenyl)-4-[[2-(4,6-dimethylpyrimidin-2-yl)hydrazinyl]methylidene]isoquinoline-1,3-dione | (4Z)-2-(3,4-dimethoxyphenyl)-4-[[N'-(4,6-dimethylpyrimidin-2-yl)hydrazino]methylene]isoquinoline-1,3-quinone | MLS001033098 | SMR000385482 | cid_5680836
Type:
Small organic molecule
Emp. Form.:
C24H23N5O4
Mol. Mass.:
445.4705
SMILES:
COc1ccc(cc1OC)-n1c(O)c(CN=Nc2nc(C)cc(C)n2)c2ccccc2c1=O |w:15.15|
Structure:
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