Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 2
Ligand
BDBM50014407
Substrate
n/a
Ki
5000±n/a nM
Comments
PDSP_1578
Citation
 Glennon, RA; Ismaiel, AE; McCarthy, BG; Peroutka, SJ Binding of arylpiperazines to 5-HT3 serotonin receptors: results of a structure-affinity study. Eur J Pharmacol 168:387-92 (1989) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 2
Synonyms:
Adrenaline alpha2 | Oct2 | Organic cation transporter 2 | S22A2_RAT | Slc22a2 | Solute carrier family 22 member 2 | rOCT2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
62348.38
Organism:
RAT
Description:
Adrenaline alpha2 0 RAT::Q9R0W2
Residue:
555
Sequence:
MSTVDDILEHIGEFHLFQKQTFFLLALLSGAFTPIYVGIVFLGFTPDHHCWSPGAAKLSQRCGWSQAEELNYTVPGLGPSDEASFLSQCMRYEVDWNQSTLDCVDPLSSLAADRNQLPLGPCEHGWVYNTPGSSIVTEFNLVCAHSWMLDLFQSVVNVGFFIGAMMIGYLADRFGRKFCLLVTILINAISGALMAISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRRMVGICYQIAFTVGLLILAGVAYVIPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKIVKAMKIIKHIAKKNGKSVPVSLQNLTPDEDAGKKLNPSFLDLVRTPQIRKHTLILMYNWFTSSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFIIILTIDRVGRRYPWAVSNMVAGAACLASVFIPDDLQWLKITIACLGRMGITMAYEMVCLVNAELYPTYIRNLGVLVCSSMCDIGGIITPFLVYRLTDIWMEFPLVVFAVVGLVAGALVLLLPETKGKALPETIEDAENMQRPRKKKEKRIYLQVKQADRPLS
  
Inhibitor
Name:
BDBM50014407
Synonyms:
2-(piperazin-1-yl)quinoline | 2-Piperazin-1-yl-quinoline | 2-Piperazin-1-yl-quinoline (Quipazine) | 2-Piperazin-1-yl-quinoline(Quipazine) | CHEMBL18772 | QUIPAZINE
Type:
Small organic molecule
Emp. Form.:
C13H15N3
Mol. Mass.:
213.2783
SMILES:
C1CN(CCN1)c1ccc2ccccc2n1
Structure:
Search PDB for entries with ligand similarity: