Reaction Details Report a problem with these data
Target
Norepinephrine transporter
Ligand
BDBM50027391
Substrate
n/a
Ki
>10000±n/a nM
Comments
PDSP_4105
Citation
 Codd, EE; Shank, RP; Schupsky, JJ; Raffa, RB Serotonin and norepinephrine uptake inhibiting activity of centrally acting analgesics: structural determinants and role in antinociception. J Pharmacol Exp Ther 274:1263-70 (1995) [PubMed] 
Target
Name:
Norepinephrine transporter
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
2082.45
Organism:
RAT
Description:
Norepinephrine transporter 0 RAT::Q9JIA2
Residue:
19
Sequence:
MLLARMKPQVQPELGGADQ
  
Inhibitor
Name:
BDBM50027391
Synonyms:
Acetic acid (1S,4S)-4-dimethylamino-1-ethyl-2,2-diphenyl-pentyl ester | Acetic acid 4-dimethylamino-1-ethyl-2,2-diphenyl-pentyl ester | Alphacetylmethadol | CHEMBL170179 | Methadyl acetate | alpha-(-)-Acetylmethadol
Type:
Small organic molecule
Emp. Form.:
C23H31NO2
Mol. Mass.:
353.4977
SMILES:
CCC(OC(C)=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1
Structure:
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