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Target
Solute carrier family 22 member 1
Ligand
BDBM29568
Substrate
n/a
Ki
0.5±n/a nM
Comments
PDSP_1528
Citation
 Schwinn, DA; Johnston, GI; Page, SO; Mosley, MJ; Wilson, KH; Worman, NP; Campbell, S; Fidock, MD; Furness, LM; Parry-Smith, DJ Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues. J Pharmacol Exp Ther 272:134-42 (1995) [PubMed] 
Target
Name:
Solute carrier family 22 member 1
Synonyms:
OCT1 | S22A1_BOVIN | SLC22A1 | adrenergic Alpha1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
62499.05
Organism:
BOVINE
Description:
adrenergic Alpha1 0 BOVINE::A7MBE0
Residue:
563
Sequence:
MLTVDDVLEQVGEFGWFQKQTFLILCLLSAAFAPIYVGIVFLAFTPDHRCRSPGVAELSRRCGWSLAEELNYTVPGPGPESQCLRYEVDWNQSTLGCLDPLASLATNGSPLPLGPCEQGWVYDTPGSSIVTEFNLVCDDSWKVDLFQSCVNLGFFLGSLGVGYIADRFGRKVCLLATTLTCASLGVLTAVAPDYTSLLIFRLLQGLVSKGSWTAGYTLITEFVGLGYRRTVAILYQMAFTVGLVLLSGLAYILPHWRWLQLAVSLPIFLLLFRFWFVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLSLEEDVTEKLSPSFIDLFRTPNLRKYTFILMYLWFTSSVVYQGLIMHVGATGGNLYLDFLYSALVEFPAGFIILVTIDRFGRRYPLATSNLAAGLACFLMIFIPHDLPWLNIMVACVGRMGITIVFQMVCLVNAELFPTFIRNLGMMVCSSLCDLGGVLTPFLVFRLMEVWQGSPLILFAALGLVAGGMTLLLPETKGVTLPETIEDAENLQRKAKPKENKIYLQVQTSELNTQAAERDASQGTAQQK
  
Inhibitor
Name:
BDBM29568
Synonyms:
CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]-Furazosin | [3H]-Minipress | [3H]-Pratsiol | [3H]-Prazosin
Type:
radiolabeled ligand
Emp. Form.:
C19H21N5O4
Mol. Mass.:
383.4011
SMILES:
COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1
Structure:
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