Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM239
Substrate
n/a
Meas. Tech.
SAR VHR1 Fluorescent Assay for In Vitro dose response studies Set 3
IC50
15600±n/a nM
Citation
 PubChem, PC SAR VHR1 Fluorescent Assay for In Vitro dose response studies Set 3 PubChem Bioassay (2011)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM239
Synonyms:
(4-methoxy-1,3-benzothiazol-2-yl)-[5-(2-thienyl)-1,3,4-oxadiazol-2-yl]amine | AB00418243-04 | AC1MMF69 | F0646-1305 | MLS-0049708.0001 | MLS-0049708.0002 | MLS000045460 | MolPort-003-038-736 | N-(4-methoxy-1,3-benzothiazol-2-yl)-5-thiophen-2-yl-1,3,4-oxadiazol-2-amine | SMR000027219 | UNM000002567502 | ZINC04110653 | cid_3237799 | potassium chloride
Type:
Small organic molecule
Emp. Form.:
C14H10N4O2S2
Mol. Mass.:
330.385
SMILES:
COc1cccc2sc(Nc3nnc(o3)-c3cccs3)nc12
Structure:
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