Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM82581
Substrate
n/a
Meas. Tech.
SAR VHR1 Fluorescent Assay for In Vitro dose response studies Set 3
IC50
12100±n/a nM
Citation
 PubChem, PC SAR VHR1 Fluorescent Assay for In Vitro dose response studies Set 3 PubChem Bioassay (2011)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM82581
Synonyms:
MLS-0098643.0002 | N-[4-(1,3-benzothiazol-2-yl)phenyl]-2-chloranyl-5-(1,2,4-triazol-4-yl)benzamide | N-[4-(1,3-benzothiazol-2-yl)phenyl]-2-chloro-5-(1,2,4-triazol-4-yl)benzamide | cid_1017691
Type:
Small organic molecule
Emp. Form.:
C22H14ClN5OS
Mol. Mass.:
431.897
SMILES:
Clc1ccc(cc1C(=O)Nc1ccc(cc1)-c1nc2ccccc2s1)-n1cnnc1
Structure:
Search PDB for entries with ligand similarity: