Reaction Details Report a problem with these data
Target
Phospholipase A2
Ligand
BDBM43254
Substrate
n/a
Meas. Tech.
Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay
IC50
502±n/a nM
Citation
 PubChem, PC Dose response counterscreen of uHTS hits for ATG4B inhibitors in a Phospholipase A2 assay PubChem Bioassay (2011)[AID] 
Target
Name:
Phospholipase A2
Synonyms:
Group IB phospholipase A2 | PA21B_HUMAN | PLA2 | PLA2A | PLA2G1B | PPLA2 | Phosphatidylcholine 2-acylhydrolase 1B | Phospholipase A2 (PLA2) | Phospholipase A2 group 1B | phospholipase A2 precursor
Type:
Protein
Mol. Mass.:
16364.13
Organism:
Homo sapiens (Human)
Description:
P04054
Residue:
148
Sequence:
MKLLVLAVLLTVAAADSGISPRAVWQFRKMIKCVIPGSDPFLEYNNYGCYCGLGGSGTPVDELDKCCQTHDNCYDQAKKLDSCKFLLDNPYTHTYSYSCSGSAITCSSKNKECEAFICNCDRNAAICFSKAPYNKAHKNLDTKKYCQS
  
Inhibitor
Name:
BDBM43254
Synonyms:
(1Z)-1-[(benzylamino)methylene]-3-nitro-6,7,8,9-tetrahydrodibenzofuran-2-one | (1Z)-1-[(benzylamino)methylidene]-3-nitro-6,7,8,9-tetrahydrodibenzofuran-2-one | (1Z)-3-nitro-1-[[(phenylmethyl)amino]methylidene]-6,7,8,9-tetrahydrodibenzofuran-2-one | 1-[(E)-Benzylimino-methyl]-3-nitro-6,7,8,9-tetrahydro-dibenzofuran-2-ol | MLS000587848 | SMR000211848 | cid_6348160
Type:
Small organic molecule
Emp. Form.:
C20H18N2O4
Mol. Mass.:
350.3679
SMILES:
[O-][N+](=O)c1cc2oc3CCCCc3c2[c-](\C=[NH+]\Cc2ccccc2)c1=O
Structure:
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