Reaction Details Report a problem with these data
Target
Endoribonuclease toxin MazF
Ligand
BDBM50650
Substrate
n/a
Meas. Tech.
Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay
EC50
80500±n/a nM
Citation
 PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay (2011)[AID] 
Target
Name:
Endoribonuclease toxin MazF
Synonyms:
MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF
Type:
Enzyme Catalytic Domain
Mol. Mass.:
12100.43
Organism:
Escherichia coli str. K-12 substr. MG1655
Description:
gi_16130689
Residue:
111
Sequence:
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
  
Inhibitor
Name:
BDBM50650
Synonyms:
6,8,9,10-tetrahydroxypyran[3,2-c]isochromene-2,3-quinone | 6,8,9,10-tetrahydroxypyrano[3,2-c][2]benzopyran-2,3-dione | 6,8,9,10-tetrahydroxypyrano[3,2-c]isochromene-2,3-dione | 6,8,9,10-tetrakis(oxidanyl)pyrano[3,2-c]isochromene-2,3-dione | Galloflavin | MLS000737267 | SMR000528495 | cid_267576
Type:
Small organic molecule
Emp. Form.:
C12H6O8
Mol. Mass.:
278.1712
SMILES:
Oc1cc2c(O)oc3cc(=O)c(=O)oc3c2c(O)c1O
Structure:
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