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Target
Sentrin-specific protease 8
Ligand
BDBM84022
Substrate
n/a
Meas. Tech.
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
IC50
5700±n/a nM
Citation
 PubChem, PC SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2 PubChem Bioassay (2011)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM84022
Synonyms:
5-bromanyl-N-(6-butyl-1,3-benzothiazol-2-yl)furan-2-carboxamide | 5-bromo-N-(6-butyl-1,3-benzothiazol-2-yl)-2-furamide | 5-bromo-N-(6-butyl-1,3-benzothiazol-2-yl)-2-furancarboxamide | 5-bromo-N-(6-butyl-1,3-benzothiazol-2-yl)furan-2-carboxamide | MLS-0437633.0002 | cid_1814490
Type:
Small organic molecule
Emp. Form.:
C16H15BrN2O2S
Mol. Mass.:
379.272
SMILES:
CCCCc1ccc2nc(NC(=O)c3ccc(Br)o3)sc2c1
Structure:
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