Reaction Details Report a problem with these data
Target
Sentrin-specific protease 8
Ligand
BDBM84106
Substrate
n/a
Meas. Tech.
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
IC50
>99000±n/a nM
Citation
 PubChem, PC SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2 PubChem Bioassay (2011)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM84106
Synonyms:
MLS-0454644.0002 | N-(6-mesyl-1,3-benzothiazol-2-yl)-4-(trifluoromethoxy)benzamide | N-(6-methylsulfonyl-1,3-benzothiazol-2-yl)-4-(trifluoromethoxy)benzamide | N-(6-methylsulfonyl-1,3-benzothiazol-2-yl)-4-(trifluoromethyloxy)benzamide | cid_16258092
Type:
Small organic molecule
Emp. Form.:
C16H11F3N2O4S2
Mol. Mass.:
416.395
SMILES:
CS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(OC(F)(F)F)cc3)sc2c1
Structure:
Search PDB for entries with ligand similarity: