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Target
Sentrin-specific protease 8
Ligand
BDBM84108
Substrate
n/a
Meas. Tech.
SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2
IC50
>99000±n/a nM
Citation
 PubChem, PC SAR Analysis of small molecule inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay - Set 2 PubChem Bioassay (2011)[AID] 
Target
Name:
Sentrin-specific protease 8
Synonyms:
DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:
Enzyme Catalytic Domain
Mol. Mass.:
24104.52
Organism:
Homo sapiens (Human)
Description:
gi_262118306
Residue:
212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQFIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDSHSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFRQQTESLLQLLTPAYITKKRGEWKDLITTLAKK
  
Inhibitor
Name:
BDBM84108
Synonyms:
MLS-0454646.0002 | N-(6-methyl-1,3-benzothiazol-2-yl)-3-(2-oxolanylmethylsulfamoyl)benzamide | N-(6-methyl-1,3-benzothiazol-2-yl)-3-(oxolan-2-ylmethylsulfamoyl)benzamide | N-(6-methyl-1,3-benzothiazol-2-yl)-3-(tetrahydrofurfurylsulfamoyl)benzamide | cid_18291044
Type:
Small organic molecule
Emp. Form.:
C20H21N3O4S2
Mol. Mass.:
431.528
SMILES:
Cc1ccc2nc(NC(=O)c3cccc(c3)S(=O)(=O)NCC3CCCO3)sc2c1
Structure:
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