Reaction Details Report a problem with these data
Target
Beta-2 adrenergic receptor
Ligand
BDBM84259
Substrate
n/a
Meas. Tech.
Dose response for HTS for Beta-2AR agonists via FAP method from CP1
EC50
5270±n/a nM
Citation
 PubChem, PC Dose response for HTS for Beta-2AR agonists via FAP method from CP1 PubChem Bioassay (2011)[AID] 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM84259
Synonyms:
2-(4-chloro-3-nitro-benzoyl)benzoic acid [2-(3-cyanoanilino)-2-keto-ethyl] ester | 2-[(4-chloro-3-nitrophenyl)-oxomethyl]benzoic acid [2-(3-cyanoanilino)-2-oxoethyl] ester | MLS000390963 | SMR000260000 | [2-(3-cyanoanilino)-2-oxoethyl] 2-(4-chloro-3-nitrobenzoyl)benzoate | [2-[(3-cyanophenyl)amino]-2-oxidanylidene-ethyl] 2-(4-chloranyl-3-nitro-phenyl)carbonylbenzoate | cid_2350847
Type:
Small organic molecule
Emp. Form.:
C23H14ClN3O6
Mol. Mass.:
463.827
SMILES:
[O-][N+](=O)c1cc(ccc1Cl)C(=O)c1ccccc1C(=O)OCC(=O)Nc1cccc(c1)C#N
Structure:
Search PDB for entries with ligand similarity: