Reaction Details Report a problem with these data
Target
Pancreatic triacylglycerol lipase
Ligand
BDBM23446
Substrate
n/a
Meas. Tech.
ChEBML_1696835
IC50
50400±n/a nM
Citation
 Jeong, GH; Cho, JH; Kim, SH; Kim, TH Plasma-induced dimerization of phloridzin as a new class of anti-adipogenic agents. Bioorg Med Chem Lett 27:4889-4892 (2017) [PubMed]  Article 
Target
Name:
Pancreatic triacylglycerol lipase
Synonyms:
LIPP_PIG | PL | PNLIP | PTL | Pancreatic lipase | Pancreatic triacylglycerol lipase
Type:
Enzyme
Mol. Mass.:
50080.69
Organism:
Sus scrofa (Pig)
Description:
P00591
Residue:
450
Sequence:
SEVCFPRLGCFSDDAPWAGIVQRPLKILPWSPKDVDTRFLLYTNQNQNNYQELVADPSTITNSNFRMDRKTRFIIHGFIDKGEEDWLSNICKNLFKVESVNCICVDWKGGSRTGYTQASQNIRIVGAEVAYFVEVLKSSLGYSPSNVHVIGHSLGSHAAGEAGRRTNGTIERITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDAAPIIPNLGFGMSQTVGHLDFFPNGGKQMPGCQKNILSQIVDIDGIWEGTRDFVACNHLRSYKYYADSILNPDGFAGFPCDSYNVFTANKCFPCPSEGCPQMGHYADRFPGKTNGVSQVFYLNTGDASNFARWRYKVSVTLSGKKVTGHILVSLFGNEGNSRQYEIYKGTLQPDNTHSDEFDSDVEVGDLQKVKFIWYNNNVINPTLPRVGASKITVERNDGKVYDFCSQETVREEVLLTLNPC
  
Inhibitor
Name:
BDBM23446
Synonyms:
3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one | CHEMBL45068 | Phloretin | cid_4788
Type:
Dihydrochalcone
Emp. Form.:
C15H14O5
Mol. Mass.:
274.2687
SMILES:
Oc1ccc(CCC(=O)c2c(O)cc(O)cc2O)cc1
Structure:
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