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Target
Reverse transcriptase
Ligand
BDBM50164644
Substrate
n/a
Meas. Tech.
ChEMBL_489999 (CHEMBL984662)
Ki
90±n/a nM
Citation
 Marchand, B; White, KL; Ly, JK; Margot, NA; Wang, R; McDermott, M; Miller, MD; Götte, M Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. Antimicrob Agents Chemother 51:2911-9 (2007) [PubMed]  Article 
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
  
Inhibitor
Name:
BDBM50164644
Synonyms:
2',3'-Dideoxyadenosine Triphosphate (Ddatp) | 2',3'-dideoxyadenosine triphosphate | ATP,2',3'-dideoxy | CHEMBL1383 | [[[5-(6-amino-9H-purin-9-yl)tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphonic acid | ddA-TP | ddATP
Type:
Small organic molecule
Emp. Form.:
C10H16N5O11P3
Mol. Mass.:
475.1822
SMILES:
Nc1ncnc2n(cnc12)[C@H]1CC[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O1 |r|
Structure:
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