Reaction Details Report a problem with these data
Target
Acetolactate synthase, chloroplastic
Ligand
BDBM50487165
Substrate
n/a
Meas. Tech.
ChEMBL_908731 (CHEMBL3066158)
Ki
25800±n/a nM
Citation
 Chen, CN; Chen, Q; Liu, YC; Zhu, XL; Niu, CW; Xi, Z; Yang, GF Syntheses and herbicidal activity of new triazolopyrimidine-2-sulfonamides as acetohydroxyacid synthase inhibitor. Bioorg Med Chem 18:4897-904 (2010) [PubMed]  Article 
Target
Name:
Acetolactate synthase, chloroplastic
Synonyms:
AHAS | ALS | Acetolactate synthase | CSR1 | ILVB_ARATH | TZP5
Type:
PROTEIN
Mol. Mass.:
72585.19
Organism:
Arabidopsis thaliana
Description:
ChEMBL_934103
Residue:
670
Sequence:
MAAATTTTTTSSSISFSTKPSPSSSKSPLPISRFSLPFSLNPNKSSSSSRRRGIKSSSPSSISAVLNTTTNVTTTPSPTKPTKPETFISRFAPDQPRKGADILVEALERQGVETVFAYPGGASMEIHQALTRSSSIRNVLPRHEQGGVFAAEGYARSSGKPGICIATSGPGATNLVSGLADALLDSVPLVAITGQVPRRMIGTDAFQETPIVEVTRSITKHNYLVMDVEDIPRIIEEAFFLATSGRPGPVLVDVPKDIQQQLAIPNWEQAMRLPGYMSRMPKPPEDSHLEQIVRLISESKKPVLYVGGGCLNSSDELGRFVELTGIPVASTLMGLGSYPCDDELSLHMLGMHGTVYANYAVEHSDLLLAFGVRFDDRVTGKLEAFASRAKIVHIDIDSAEIGKNKTPHVSVCGDVKLALQGMNKVLENRAEELKLDFGVWRNELNVQKQKFPLSFKTFGEAIPPQYAIKVLDELTDGKAIISTGVGQHQMWAAQFYNYKKPRQWLSSGGLGAMGFGLPAAIGASVANPDAIVVDIDGDGSFIMNVQELATIRVENLPVKVLLLNNQHLGMVMQWEDRFYKANRAHTFLGDPAQEDEIFPNMLLFAAACGIPAARVTKKADLREAIQTMLDTPGPYLLDVICPHQEHVLPMIPSGGTFNDVITEGDGRIKY
  
Inhibitor
Name:
BDBM50487165
Synonyms:
CHEMBL2251943
Type:
Small organic molecule
Emp. Form.:
C13H11ClFN5O2S
Mol. Mass.:
355.775
SMILES:
Cc1nc(C)n2nc(nc2c1Cl)S(=O)(=O)Nc1ccccc1F
Structure:
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