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Target
Acyl-protein thioesterase 2
Ligand
BDBM50496625
Substrate
n/a
Meas. Tech.
ChEMBL_1300904 (CHEMBL3135191)
IC50
200±n/a nM
Citation
 Davda, D; Martin, BR Acyl protein thioesterase inhibitors as probes of dynamic S-palmitoylation. Medchemcomm 5:268-276 (2014) [PubMed]  Article 
Target
Name:
Acyl-protein thioesterase 2
Synonyms:
APT2 | Acyl-protein thioesterase 2 (APT2 WT) | LYPA2_HUMAN | LYPLA2 | Lysophospholipase II
Type:
Protein
Mol. Mass.:
24740.23
Organism:
Homo sapiens (Human)
Description:
O95372
Residue:
231
Sequence:
MCGNTMSVPLLTDAATVSGAERETAAVIFLHGLGDTGHSWADALSTIRLPHVKYICPHAPRIPVTLNMKMVMPSWFDLMGLSPDAPEDEAGIKKAAENIKALIEHEMKNGIPANRIVLGGFSQGGALSLYTALTCPHPLAGIVALSCWLPLHRAFPQAANGSAKDLAILQCHGELDPMVPVRFGALTAEKLRSVVTPARVQFKTYPGVMHSSCPQEMAAVKEFLEKLLPPV
  
Inhibitor
Name:
BDBM50496625
Synonyms:
CHEMBL3133033
Type:
Small organic molecule
Emp. Form.:
C21H22N4O2
Mol. Mass.:
362.425
SMILES:
OC(c1cnn(n1)C(=O)N1CCCCC1)(c1ccccc1)c1ccccc1
Structure:
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