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Target
Actin, alpha skeletal muscle
Ligand
BDBM50508923
Substrate
n/a
Meas. Tech.
ChEMBL_1835666 (CHEMBL4335799)
IC50
8470±n/a nM
Citation
 Wang, S; Gegenfurtner, FA; Crevenna, AH; Ziegenhain, C; Kliesmete, Z; Enard, W; Müller, R; Vollmar, AM; Schneider, S; Zahler, S Chivosazole A Modulates Protein-Protein Interactions of Actin. J Nat Prod 82:1961-1970 (2019) [PubMed]  Article 
Target
Name:
Actin, alpha skeletal muscle
Synonyms:
ACTA | ACTA1 | ACTS_RABIT | Actin, alpha skeletal muscle | Actin, alpha skeletal muscle, intermediate form | Alpha-actin-1
Type:
PROTEIN
Mol. Mass.:
42042.02
Organism:
Oryctolagus cuniculus
Description:
ChEMBL_119010
Residue:
377
Sequence:
MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF
  
Inhibitor
Name:
BDBM50508923
Synonyms:
CHEBI:49703 | LATRUNCULIN B | NSC-339663
Type:
Small organic molecule
Emp. Form.:
C20H29NO5S
Mol. Mass.:
395.513
SMILES:
[H][C@]1(CSC(=O)N1)[C@@]1(O)C[C@@]2([H])C[C@@]([H])(CC[C@H](C)\C=C/CC\C(C)=C/C(=O)O2)O1 |r,c:20,25|
Structure:
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