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TargetActin, alpha skeletal muscle
LigandBDBM50508923
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1835666
IC50 8470±n/a nM
Citation Wang, SGegenfurtner, FACrevenna, AHZiegenhain, CKliesmete, ZEnard, WMüller, RVollmar, AMSchneider, SZahler, S Chivosazole A Modulates Protein-Protein Interactions of Actin. J Nat Prod82:1961-1970 (2019) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Actin, alpha skeletal muscle
Name:Actin, alpha skeletal muscle
Synonyms:ACTA | ACTA1 | Actin, alpha skeletal muscle | Actin, alpha skeletal muscle, intermediate form | Alpha-actin-1
Type:PROTEIN
Mol. Mass.:42042.02
Organism:Oryctolagus cuniculus
Description:ChEMBL_119010
Residue:377
Sequence:
MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEA
QSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREK
MTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRL
DLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEK
SYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNV
MSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWIT
KQEYDEAGPSIVHRKCF
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50508923
NameBDBM50508923
Synonyms:CHEBI:49703 | LATRUNCULIN B | NSC-339663
TypeSmall organic molecule
Emp. Form.C20H29NO5S
Mol. Mass.395.513
SMILES[H][C@]1(CSC(=O)N1)[C@@]1(O)C[C@@]2([H])C[C@@]([H])(CC[C@H](C)\C=C/CC\C(C)=C/C(=O)O2)O1 |r,c:20,25|
Structure
n/a