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Target
Mu-type opioid receptor
Ligand
BDBM50045772
Substrate
n/a
Meas. Tech.
ChEMBL_221928 (CHEMBL842493)
Ki
80±n/a nM
Citation
 Thomas, JB; Mascarella, SW; Burgess, JP; Xu, H; McCullough, KB; Rothman, RB; Flippen-Anderson, JL; George, CF; Cantrell, BE; Zimmerman, DM; Carroll, FI N-substituted octahydro-4a-(3-hydroxyphenyl)-10a-methyl-benzo[g]isoquinolines are opioid receptor pure antagonists. Bioorg Med Chem Lett 8:3149-52 (1999) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50045772
Synonyms:
3-((3R,4R)-1,3,4-Trimethyl-piperidin-4-yl)-phenol | 3-(1,3,4-Trimethyl-piperidin-4-yl)-phenol | CHEMBL318723
Type:
Small organic molecule
Emp. Form.:
C14H21NO
Mol. Mass.:
219.3226
SMILES:
C[C@H]1CN(C)CC[C@@]1(C)c1cccc(O)c1
Structure:
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