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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM50118961
Substrate
n/a
Meas. Tech.
ChEBML_159288
IC50
0.100000±n/a nM
Citation
 Raghavan, S; Yang, Z; Mosley, RT; Schleif, WA; Gabryelski, L; Olsen, DB; Stahlhut, M; Kuo, LC; Emini, EA; Chapman, KT; Tata, JR Combinatorial library of indinavir analogues: replacement for the aminoindanol at P2'. Bioorg Med Chem Lett 12:2855-8 (2002) [PubMed]  Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50118961
Synonyms:
(R)-1-[(3R,5R)-2-Hydroxy-4-((R)-2-hydroxy-indan-1-ylcarbamoyl)-5-phenyl-pentyl]-4-(thiophene-2-sulfonyl)-piperazine-2-carboxylic acid tert-butylamide | CHEMBL95611
Type:
Small organic molecule
Emp. Form.:
C34H44N4O6S2
Mol. Mass.:
668.866
SMILES:
CC(C)(C)NC(=O)[C@H]1CN(CCN1C[C@H](O)C[C@@H](Cc1ccccc1)C(=O)NC1[C@H](O)Cc2ccccc12)S(=O)(=O)c1cccs1
Structure:
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