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Target
Alpha-1D adrenergic receptor
Ligand
BDBM50186610
Substrate
n/a
Meas. Tech.
ChEMBL_353199 (CHEMBL865719)
EC50
3300±n/a nM
Citation
 Boschi, D; Tron, GC; Lazzarato, L; Chegaev, K; Cena, C; Di Stilo, A; Giorgis, M; Bertinaria, M; Fruttero, R; Gasco, A NO-donor phenols: a new class of products endowed with antioxidant and vasodilator properties. J Med Chem 49:2886-97 (2006) [PubMed]  Article 
Target
Name:
Alpha-1D adrenergic receptor
Synonyms:
ADA1D_RAT | Adra1a | Adra1d | Alpha adrenergic receptor 1A and 1D | Alpha-1D adrenergic receptor | Serotonin 1a (5-HT1a) receptor/Adrenergic receptor alpha-1
Type:
Protein
Mol. Mass.:
59375.97
Organism:
Rattus norvegicus (Rat)
Description:
P23944
Residue:
561
Sequence:
MTFRDILSVTFEGPRSSSSTGGSGAGGGAGTVGPEGGAVGGVPGATGGGAVVGTGSGEDNQSSTGEPGAAASGEVNGSAAVGGLVVSAQGVGVGVFLAAFILTAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSAAVLPFSATMEVLGFWAFGRTFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWAVALVVSVGPLLGWKEPVPPDERFCGITEEVGYAIFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGIKREPGKASEVVLRIHCRGAATSAKGYPGTQSSKGHTLRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRRRLWAVYGHHWRASTGDARSDCAPSPRIAPPGAPLALTAHPGAGSADTPETQDSVSSSRKPASALREWRLLGPLQRPTTQLRAKVSSLSHKIRSGARRAETACALRSEVEAVSLNVPQDGAEAVICQAYEPGDYSNLRETDI
  
Inhibitor
Name:
BDBM50186610
Synonyms:
3-((4-hydroxy-3,5-di-tert-butyl)phenyl)prop-1,2-diyl dinitrate | CHEMBL381519
Type:
Small organic molecule
Emp. Form.:
C17H26N2O6
Mol. Mass.:
354.3981
SMILES:
CC(C)(C)c1cc(CC(CO[N+]([O-])=O)[N+]([O-])=O)cc(c1O)C(C)(C)C
Structure:
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