Reaction Details Report a problem with these data
Target
Carbonic anhydrase 3
Ligand
BDBM50323751
Substrate
n/a
Meas. Tech.
ChEMBL_646955 (CHEMBL1217096)
Ki
48000±n/a nM
Citation
 Carta, F; Temperini, C; Innocenti, A; Scozzafava, A; Kaila, K; Supuran, CT Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule. J Med Chem 53:5511-22 (2010) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 3
Synonyms:
CA-III | CA3 | CAH3_HUMAN | Carbonate dehydratase III | Carbonic Anhydrase III | Carbonic anhydrase | Carbonic anhydrase 3 (CA III) | Carbonic anhydrase III (CA III)
Type:
Enzyme
Mol. Mass.:
29562.11
Organism:
Homo sapiens (Human)
Description:
Human cloned isozyme.
Residue:
260
Sequence:
MAKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDPSCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSNWRPPQPINNRVVRASFK
  
Inhibitor
Name:
BDBM50323751
Synonyms:
CHEMBL609 | N,N'-BIS(2-AMINOETHYL)-1,2-ETHANEDIAMINE | N,N'-Bis-(2-amino-ethyl)-ethane-1,2-diamine | Syprine | TRIENTINE | triethylenetetramine
Type:
Small organic molecule
Emp. Form.:
C6H18N4
Mol. Mass.:
146.2339
SMILES:
NCCNCCNCCN
Structure:
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