Reaction Details Report a problem with these data
Target
Zn finger protein
Ligand
BDBM50300203
Substrate
n/a
Meas. Tech.
ChEMBL_687568 (CHEMBL1290840)
Ki
48.6±n/a nM
Citation
Maresca, A; Scozzafava, A; Supuran, CT 7,8-disubstituted- but not 6,7-disubstituted coumarins selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II in the low nanomolar/subnanomolar range. Bioorg Med Chem Lett 20:7255-8 (2010) [PubMed] Article
More Info.:
Target
Name:
Zn finger protein
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
25827.13
Organism:
Nicotiana tabacum
Description:
ChEMBL_687568
Residue:
234
Sequence:
LPLPFFNMDTSHWPQGIGLAKAVEPSKPVPVTERKPRPQKEQAINCPRCNSTNTKFCYYNNYSLSQPRYFCKTCRRYWTDGGSLRNVPVGGGSRKNKRSNSSSNNSSSSTSSSYKKIPDLTIPTSSSTQNPKIINEPHDLNLTFNPSTTSNFSNISEFMALPLMNPNSTTSFMSSIMPQISDSNNIMYSSSSTGLPNLHDLKPTLNFSLDGFDNNNGYGSLQGETAGAKLFFPL