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Target
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5
Ligand
BDBM92459
Substrate
n/a
Meas. Tech.
ChEBML_69264
IC50
67000±n/a nM
Citation
 Schuster, M; Blechert, S Inhibition of fucosyltransferase V by a GDP-Azasugar. Bioorg Med Chem Lett 11:1809-11 (2001) [PubMed]  Article 
Target
Name:
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5
Synonyms:
FUT5 | FUT5_HUMAN | Fucosyltransferase 5
Type:
PROTEIN
Mol. Mass.:
43016.71
Organism:
Homo sapiens (Human)
Description:
ChEMBL_69264
Residue:
374
Sequence:
MDPLGPAKPQWLWRRCLAGLLFQLLVAVCFFSYLRVSRDDATGSPRPGLMAVEPVTGAPNGSRCQDSMATPAHPTLLILLWTWPFNTPVALPRCSEMVPGAADCNITADSSVYPQADAVIVHHWDIMYNPSANLPPPTRPQGQRWIWFSMESPSNCRHLEALDGYFNLTMSYRSDSDIFTPYGWLEPWSGQPAHPPLNLSAKTELVAWAVSNWKPDSARVRYYQSLQAHLKVDVYGRSHKPLPKGTMMETLSRYKFYLAFENSLHPDYITEKLWRNALEAWAVPVVLGPSRSNYERFLPPDAFIHVDDFQSPKDLARYLQELDKDHARYLSYFRWRETLRPRSFSWALAFCKACWKLQQESRYQTVRSIAAWFT
  
Inhibitor
Name:
BDBM92459
Synonyms:
CHEMBL384759 | GDP | Guanosine Diphosphate
Type:
Small molecule
Emp. Form.:
C10H15N5O11P2
Mol. Mass.:
443.2005
SMILES:
Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O
Structure:
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