Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 6
Ligand
BDBM50206509
Substrate
n/a
Meas. Tech.
ChEMBL_508179 (CHEMBL1008237)
Ki
6310±n/a nM
Citation
 Kaler, G; Truong, DM; Khandelwal, A; Nagle, M; Eraly, SA; Swaan, PW; Nigam, SK Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members. J Biol Chem 282:23841-53 (2007) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 6
Synonyms:
Nkt | Oat1 | S22A6_MOUSE | Slc22a6
Type:
PROTEIN
Mol. Mass.:
60032.49
Organism:
Mus musculus
Description:
ChEMBL_508179
Residue:
545
Sequence:
MAFNDLLKQVGGVGRFQLIQVTMVVAPLLLMASHNTLQNFTAAIPAHHCRPPANANLSKDGGLEAWLPLDKQGRPESCLRFPFPHNGTEANGTGVTEPCLDGWVYDNSTFPSTIVTEWNLVCSHRAFRQLAQSLFMVGVLLGAMMFGYLADRLGRRKVLILNYLQTAVSGTCAAYAPNYTVYCIFRLLSGMSLASIAINCMTLNMEWMPIHTRAYVGTLIGYVYSLGQFLLAGIAYAVPHWRHLQLAVSVPFFVAFIYSWFFIESARWYSSSGRLDLTLRALQRVARINGKQEEGAKLSIEVLQTSLQKELTLNKGQASAMELLRCPTLRRLFLCLSMLWFATSFAYYGLVMDLQGFGVSMYLIQVIFGAVDLPAKFVCFLVINSMGRRPAQLASLLLAGICILVNGIIPRGHTIIRTSLAVLGKGCLASSFNCIFLYTGELYPTMIRQTGLGMGSTMARVGSIVSPLISMTAEFYPSIPLFIFGAVPVAASAVTALLPETLGQPLPDTVQDLKSRSRGKQKQQQLEQQKQMIPLQVSTQEKNGL
  
Inhibitor
Name:
BDBM50206509
Synonyms:
4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfamoyl-benzoic acid anion | 4-Dipropylsulfamoyl-benzoic acid(probenecid) | Benemid | CHEMBL897 | PROBENECID | Probalan
Type:
Small organic molecule
Emp. Form.:
C13H19NO4S
Mol. Mass.:
285.359
SMILES:
CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O
Structure:
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