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Target
Beta-2 adrenergic receptor
Ligand
BDBM25749
Substrate
n/a
Meas. Tech.
ChEMBL_38009 (CHEMBL655219)
Kd
1584.89±n/a nM
Citation
 Erhardt, PW; Woo, CM; Anderson, WG; Gorczynski, RJ Ultra-short-acting beta-adrenergic receptor blocking agents. 2. (Aryloxy)propanolamines containing esters on the aryl function. J Med Chem 25:1408-12 (1983) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2_CAVPO | Adrb2 | adrenergic Beta2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46993.24
Organism:
GUINEA PIG
Description:
adrenergic Beta2 ADRB2 GUINEA PIG::Q8K4Z4
Residue:
418
Sequence:
MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKDAINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRFHTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNGKTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
  
Inhibitor
Name:
BDBM25749
Synonyms:
CHEMBL6995 | N-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}acetamide | Practolol | Practolol,(+) | Practolol,(-)
Type:
Small organic molecule
Emp. Form.:
C14H22N2O3
Mol. Mass.:
266.3361
SMILES:
CC(C)NCC(O)COc1ccc(NC(C)=O)cc1
Structure:
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