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TargetCarbonic anhydrase 2
LigandBDBM50415863
Substrate/Competitorn/a
Meas. Tech.ChEMBL_632192
Ki 109±n/a nM
Citation Sethi, KKVerma, SMPrasanthi, NSahoo, SKParhi, RNSuresh, P 3D-QSAR study of benzene sulfonamide analogs as carbonic anhydrase II inhibitors. Bioorg Med Chem Lett20:3089-93 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 2
Name:Carbonic anhydrase 2
Synonyms:CA-II | CA2 | CAC | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:Enzyme
Mol. Mass.:29250.71
Organism:Homo sapiens (Human)
Description:P00918
Residue:260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRIL
NNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL
VHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDP
RGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELM
VDNWRPAQPLKNRQIKASFK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50415863
NameBDBM50415863
Synonyms:CHEMBL358263
TypeSmall organic molecule
Emp. Form.C8H11NO2S
Mol. Mass.185.243
SMILESCCc1ccc(cc1)S(N)(=O)=O
Structure
n/a