Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 7
Ligand
BDBM50206509
Substrate
n/a
Meas. Tech.
ChEMBL_836101 (CHEMBL2077537)
Ki
766000±n/a nM
Citation
 Enomoto, A; Takeda, M; Shimoda, M; Narikawa, S; Kobayashi, Y; Kobayashi, Y; Yamamoto, T; Sekine, T; Cha, SH; Niwa, T; Endou, H Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors. J Pharmacol Exp Ther 301:797-802 (2002) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 7
Synonyms:
NLT | Novel liver transporter | OAT2 | Organic anion transporter 2 | S22A7_HUMAN | SLC22A7 | hOAT2
Type:
PROTEIN
Mol. Mass.:
60027.96
Organism:
Homo sapiens (Human)
Description:
ChEMBL_836101
Residue:
548
Sequence:
MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSHQDVWLEAHLPREPDGTLSSCLRFAYPQALPNTTLGEERQSRGELEDEPATVPCSQGWEYDHSEFSSTIATESQWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVAYVSTLVLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLELEWLDVEHRTVAGVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVKEAHRYLLHCARLNGRPVCEDSFSQEAVSKVAAGERVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTRLLVSSDMKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVERKSAPTSLQEEEMPMKQVQN
  
Inhibitor
Name:
BDBM50206509
Synonyms:
4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfamoyl-benzoic acid anion | 4-Dipropylsulfamoyl-benzoic acid(probenecid) | Benemid | CHEMBL897 | PROBENECID | Probalan
Type:
Small organic molecule
Emp. Form.:
C13H19NO4S
Mol. Mass.:
285.359
SMILES:
CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(O)=O
Structure:
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