Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 6
Ligand
BDBM50344964
Substrate
n/a
Meas. Tech.
ChEMBL_836138 (CHEMBL2077574)
Ki
23600±n/a nM
Citation
 Takeda, M; Narikawa, S; Hosoyamada, M; Cha, SH; Sekine, T; Endou, H Characterization of organic anion transport inhibitors using cells stably expressing human organic anion transporters. Eur J Pharmacol 419:113-20 (2001) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 6
Synonyms:
OAT1 | Organic anion transporter 1 | PAH transporter | PAHT | Renal organic anion transporter 1 | S22A6_HUMAN | SLC22A6 | hOAT1 | hPAHT | hROAT1
Type:
PROTEIN
Mol. Mass.:
61831.78
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1487359
Residue:
563
Sequence:
MAFNDLLQQVGGVGRFQQIQVTLVVLPLLLMASHNTLQNFTAAIPTHHCRPPADANLSKNGGLEVWLPRDRQGQPESCLRFTSPQWGLPFLNGTEANGTGATEPCTDGWIYDNSTFPSTIVTEWDLVCSHRALRQLAQSLYMVGVLLGAMVFGYLADRLGRRKVLILNYLQTAVSGTCAAFAPNFPIYCAFRLLSGMALAGISLNCMTLNVEWMPIHTRACVGTLIGYVYSLGQFLLAGVAYAVPHWRHLQLLVSAPFFAFFIYSWFFIESARWHSSSGRLDLTLRALQRVARINGKREEGAKLSMEVLRASLQKELTMGKGQASAMELLRCPTLRHLFLCLSMLWFATSFAYYGLVMDLQGFGVSIYLIQVIFGAVDLPAKLVGFLVINSLGRRPAQMAALLLAGICILLNGVIPQDQSIVRTSLAVLGKGCLAASFNCIFLYTGELYPTMIRQTGMGMGSTMARVGSIVSPLVSMTAELYPSMPLFIYGAVPVAASAVTVLLPETLGQPLPDTVQDLESRWAPTQKEAGIYPRKGKQTRQQQEHQKYMVPLQASAQEKNGL
  
Inhibitor
Name:
BDBM50344964
Synonyms:
Betamipron | CHEMBL1231530 | N-(phenylcarbonyl)-beta-alanine
Type:
Small organic molecule
Emp. Form.:
C10H11NO3
Mol. Mass.:
193.1992
SMILES:
OC(=O)CCNC(=O)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: