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Target
Oligo-1,6-glucosidase IMA1
Ligand
BDBM50341204
Substrate
n/a
Meas. Tech.
ChEMBL_947690 (CHEMBL2341129)
Ki
4860±n/a nM
Citation
 Mata, R; Cristians, S; Escandón-Rivera, S; Juárez-Reyes, K; Rivero-Cruz, I Mexican antidiabetic herbs: valuable sources of inhibitors ofa-glucosidases. J Nat Prod 76:468-83 (2013) [PubMed]  Article 
Target
Name:
Oligo-1,6-glucosidase IMA1
Synonyms:
α-glucosidase | Alpha-glucosidase | Alpha-glucosidase (α-glucosidase) | IMA1 | MALX3_YEAST | Oligo-1,6-glucosidase
Type:
Protein
Mol. Mass.:
68577.59
Organism:
Saccharomyces cerevisiae S288c (Baker's yeast)
Description:
n/a
Residue:
589
Sequence:
MTISSAHPETEPKWWKEATFYQIYPASFKDSNDDGWGDMKGIASKLEYIKELGADAIWISPFYDSPQDDMGYDIANYEKVWPTYGTNEDCFALIEKTHKLGMKFITDLVINHCSSEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSYFGGSAWTFDEKTQEFYLRLFCSTQPDLNWENEDCRKAIYESAVGYWLDHGVDGFRIDVGSLYSKVVGLPDAPVVDKNSTWQSSDPYTLNGPRIHEFHQEMNQFIRNRVKDGREIMTVGEMQHASDETKRLYTSASRHELSELFNFSHTDVGTSPLFRYNLVPFELKDWKIALAELFRYINGTDCWSTIYLENHDQPRSITRFGDDSPKNRVISGKLLSVLLSALTGTLYVYQGQELGQINFKNWPVEKYEDVEIRNNYNAIKEEHGENSEEMKKFLEAIALISRDHARTPMQWSREEPNAGFSGPSAKPWFYLNDSFREGINVEDEIKDPNSVLNFWKEALKFRKAHKDITVYGYDFEFIDLDNKKLFSFTKKYNNKTLFAALNFSSDATDFKIPNDDSSFKLEFGNYPKKEVDASSRTLKPWEGRIYISE
  
Inhibitor
Name:
BDBM50341204
Synonyms:
(Z)-3-butylidenephthalide | CHEMBL1765390
Type:
Small organic molecule
Emp. Form.:
C12H12O2
Mol. Mass.:
188.2225
SMILES:
CCC\C=C1\OC(=O)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: