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Target
P2X purinoceptor 1
Ligand
BDBM50102295
Substrate
n/a
Meas. Tech.
ChEMBL_1280016 (CHEMBL3096843)
IC50
30±n/a nM
Citation
 Cho, JH; Jung, KY; Jung, Y; Kim, MH; Ko, H; Park, CS; Kim, YC Design and synthesis of potent and selective P2X3 receptor antagonists derived from PPADS as potential pain modulators. Eur J Med Chem 70:811-30 (2013) [PubMed]  Article 
Target
Name:
P2X purinoceptor 1
Synonyms:
P2RX1_MOUSE | P2rx1
Type:
PROTEIN
Mol. Mass.:
44863.39
Organism:
Mus musculus
Description:
ChEMBL_1280016
Residue:
399
Sequence:
MARRLQDELSAFFFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFVYEKGYQTSSGLISSVSVKLKGLAVTQLQGLGPQVWDVADYVFPAHGDSSFVVMTNFIMTPQQAQGHCAENPEGGICQDDSGCTPGKAERKAQGIRTGNCVPFNGTVKTCEIFGWCPVEVDDKIPSPALLHEAENFTLFIKNSISFPRFKVNRRNLVEEVNGTYMKKCLYHKILHPLCPVFSLGYVVRESGQDFRSLAEKGGVVGITIDWECDLDWHVRHCKPIYQFHGLYGEKNLSPGFNFRFARHFVQNGTNRRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKRHYYKQKKFKYAEDMGPGEGERDPAATSSTLGLQENMRTS
  
Inhibitor
Name:
BDBM50102295
Synonyms:
4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethyl-pyridin-2-ylazo)-benzoic acid | CHEMBL119235
Type:
Small organic molecule
Emp. Form.:
C15H14N3O8P
Mol. Mass.:
395.2607
SMILES:
Cc1nc(N=Nc2ccc(cc2)C(O)=O)c(COP(O)(O)=O)c(C=O)c1O |w:5.5|
Structure:
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