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Target
Mu-type opioid receptor
Ligand
BDBM50025234
Substrate
n/a
Meas. Tech.
ChEMBL_1431190 (CHEMBL3385053)
Ki
284±n/a nM
Citation
 Polepally, PR; Huben, K; Vardy, E; Setola, V; Mosier, PD; Roth, BL; Zjawiony, JK Michael acceptor approach to the design of new salvinorin A-based high affinity ligands for the kappa-opioid receptor. Eur J Med Chem 85:818-29 (2014) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50025234
Synonyms:
CHEMBL3330664
Type:
Small organic molecule
Emp. Form.:
C26H32O8
Mol. Mass.:
472.5275
SMILES:
[H][C@@]12[#6]-[#6][C@@]3([#6])[#6@@H](-[#6]-[#6@H](-[#8]-[#6](=O)\[#6]=[#6](\[#6])-[#6])-[#6](=O)[C@]3([H])[C@@]1([#6])[#6]-[#6@H](-[#8]-[#6]2=O)-c1ccoc1)-[#6](=O)-[#8]-[#6] |r|
Structure:
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