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Target
Sporulation kinase A
Ligand
BDBM50218659
Substrate
n/a
Meas. Tech.
ChEMBL_92581 (CHEMBL700426)
IC50
17000±n/a nM
Citation
 Weidner-Wells, MA; Ohemeng, KA; Nguyen, VN; Fraga-Spano, S; Macielag, MJ; Werblood, HM; Foleno, BD; Webb, GC; Barrett, JF; Hlasta, DJ Amidino benzimidazole inhibitors of bacterial two-component systems. Bioorg Med Chem Lett 11:1545-8 (2001) [PubMed]  Article 
Target
Name:
Sporulation kinase A
Synonyms:
KINA_BACSU | Sporulation kinase A | Stage II sporulation protein F | Stage II sporulation protein J | gsiC | kinA | scoD | spoIIF | spoIIJ
Type:
PROTEIN
Mol. Mass.:
69161.05
Organism:
Bacillus subtilis (strain 168)
Description:
ChEMBL_105028
Residue:
606
Sequence:
MEQDTQHVKPLQTKTDIHAVLASNGRIIYISANSKLHLGYLQGEMIGSFLKTFLHEEDQFLVESYFYNEHHLMPCTFRFIKKDHTIVWVEAAVEIVTTRAERTEREIILKMKVLEEETGHQSLNCEKHEIEPASPESTTYITDDYERLVENLPSPLCISVKGKIVYVNSAMLSMLGAKSKDAIIGKSSYEFIEEEYHDIVKNRIIRMQKGMEVGMIEQTWKRLDGTPVHLEVKASPTVYKNQQAELLLLIDISSRKKFQTILQKSRERYQLLIQNSIDTIAVIHNGKWVFMNESGISLFEAATYEDLIGKNIYDQLHPCDHEDVKERIQNIAEQKTESEIVKQSWFTFQNRVIYTEMVCIPTTFFGEAAVQVILRDISERKQTEELMLKSEKLSIAGQLAAGIAHEIRNPLTAIKGFLQLMKPTMEGNEHYFDIVFSELSRIELILSELLMLAKPQQNAVKEYLNLKKLIGEVSALLETQANLNGIFIRTSYEKDSIYINGDQNQLKQVFINLIKNAVESMPDGGTVDIIITEDEHSVHVTVKDEGEGIPEKVLNRIGEPFLTTKEKGTGLGLMVTFNIIENHQGVIHVDSHPEKGTAFKISFPKK
  
Inhibitor
Name:
BDBM50218659
Synonyms:
CHEMBL43691
Type:
Small organic molecule
Emp. Form.:
C26H21N5
Mol. Mass.:
403.4784
SMILES:
NC(=N)c1ccc2[nH]c(nc2c1)-c1ccc(cc1)N(c1ccccc1)c1ccccc1
Structure:
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