Reaction Details Report a problem with these data
Target
Melanocortin receptor 4
Ligand
BDBM88442
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>89200±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88442
Synonyms:
MLS000573251 | N-({[3-(benzoylamino)phenyl]amino}carbonothioyl)-2-thiophenecarboxamide | N-[(3-benzamidoanilino)-sulfanylidenemethyl]-2-thiophenecarboxamide | N-[(3-benzamidophenyl)carbamothioyl]thiophene-2-carboxamide | N-[(3-benzamidophenyl)thiocarbamoyl]thiophene-2-carboxamide | SMR000194752 | cid_1349192
Type:
Small organic molecule
Emp. Form.:
C19H15N3O2S2
Mol. Mass.:
381.471
SMILES:
O=C(NC(=S)Nc1cccc(NC(=O)c2ccccc2)c1)c1cccs1
Structure:
Search PDB for entries with ligand similarity: