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Target
Melanocortin receptor 4
Ligand
BDBM79374
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R)
EC50
>89188±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for biased ligands (agonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM79374
Synonyms:
MLS002473616 | N,N-dimethyl-2-[4-(2-thiophen-3-yl-1-benzothiophen-3-yl)phenoxy]ethanamine | N,N-dimethyl-2-[4-[2-(3-thiophenyl)-1-benzothiophen-3-yl]phenoxy]ethanamine | SMR001397783 | cid_44202260 | dimethyl-[2-[4-[2-(3-thienyl)benzothiophen-3-yl]phenoxy]ethyl]amine
Type:
Small organic molecule
Emp. Form.:
C22H21NOS2
Mol. Mass.:
379.538
SMILES:
CN(C)CCOc1ccc(cc1)-c1c(sc2ccccc12)-c1ccsc1
Structure:
Search PDB for entries with ligand similarity: