Reaction Details Report a problem with these data
Target
Melanocortin receptor 4
Ligand
BDBM88579
Substrate
n/a
Meas. Tech.
TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R)
IC50
>64575±n/a nM
Citation
 PubChem, PC TRFRET-based cell-based high throughput dose response assay for biased ligands (antagonists) of the melanocortin 4 receptor (MC4R) PubChem Bioassay (2012)[AID] 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R)
Type:
Enzyme
Mol. Mass.:
36949.50
Organism:
Homo sapiens (Human)
Description:
P32245
Residue:
332
Sequence:
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICCYPLGGLCDLSSRY
  
Inhibitor
Name:
BDBM88579
Synonyms:
2-[[5-[4-[(2-chlorobenzyl)sulfamoyl]phenyl]-1,3,4-oxadiazol-2-yl]thio]acetic acid methyl ester | 2-[[5-[4-[(2-chlorophenyl)methylsulfamoyl]phenyl]-1,3,4-oxadiazol-2-yl]thio]acetic acid methyl ester | MLS000122835 | SMR000123462 | cid_1155311 | methyl 2-[[5-[4-[(2-chlorophenyl)methylsulfamoyl]phenyl]-1,3,4-oxadiazol-2-yl]sulfanyl]acetate | methyl 2-[[5-[4-[(2-chlorophenyl)methylsulfamoyl]phenyl]-1,3,4-oxadiazol-2-yl]sulfanyl]ethanoate | {5-[4-(2-Chloro-benzylsulfamoyl)-phenyl]-[1,3,4]oxadiazol-2-ylsulfanyl}-acetic acid methyl ester
Type:
Small organic molecule
Emp. Form.:
C18H16ClN3O5S2
Mol. Mass.:
453.92
SMILES:
COC(=O)CSc1nnc(o1)-c1ccc(cc1)S(=O)(=O)NCc1ccccc1Cl
Structure:
Search PDB for entries with ligand similarity: