Reaction Details Report a problem with these data
Target
Tyrosine-protein phosphatase non-receptor type 5
Ligand
BDBM82886
Substrate
n/a
Meas. Tech.
Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay
IC50
>80000±n/a nM
Citation
 PubChem, PC Dose response confirmation of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a fluorescence intensity assay PubChem Bioassay (2012)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 5
Synonyms:
PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
63510.68
Organism:
Homo sapiens (Human)
Description:
gi_90652859
Residue:
565
Sequence:
MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPPPPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLVSSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQSPE
  
Inhibitor
Name:
BDBM82886
Synonyms:
3-(1,3-benzodioxol-5-yl)-N-[(4-fluorobenzylidene)amino]-1H-pyrazole-5-carboxamide | 3-(1,3-benzodioxol-5-yl)-N-[(4-fluorophenyl)methylideneamino]-1H-pyrazole-5-carboxamide | 3-(1,3-benzodioxol-5-yl)-N-[(E)-(4-fluorobenzylidene)amino]-1H-pyrazole-5-carboxamide | 5-Benzo[1,3]dioxol-5-yl-2H-pyrazole-3-carboxylic acid [1-(4-fluoro-phenyl)-meth-(E)-ylidene]-hydrazide | MLS000769222 | SMR000433956 | cid_1539182
Type:
Small organic molecule
Emp. Form.:
C18H13FN4O3
Mol. Mass.:
352.3192
SMILES:
Fc1ccc(C=NNC(=O)c2cc(n[nH]2)-c2ccc3OCOc3c2)cc1 |w:6.6|
Structure:
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