Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM88759
Substrate
n/a
Meas. Tech.
Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay
IC50
3070±n/a nM
Citation
 PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay (2012)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM88759
Synonyms:
MLS000664771 | N-cycloheptyl-2-(cyclohexylamino)-2-sulfanylidene-ethanamide | N-cycloheptyl-2-(cyclohexylamino)-2-sulfanylideneacetamide | N-cycloheptyl-2-(cyclohexylamino)-2-thioxo-acetamide | N-cycloheptyl-2-(cyclohexylamino)-2-thioxoacetamide | SMR000296231 | cid_2974583
Type:
Small organic molecule
Emp. Form.:
C15H26N2OS
Mol. Mass.:
282.445
SMILES:
O=C(NC1CCCCCC1)C(=S)NC1CCCCC1
Structure:
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