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Target
Dual specificity protein phosphatase 3
Ligand
BDBM82870
Substrate
n/a
Meas. Tech.
Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay
IC50
4250±n/a nM
Citation
 PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay (2012)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM82870
Synonyms:
2-(4-nitrophenoxy)-N-(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)acetamide | 2-(4-nitrophenoxy)-N-(5-pyridin-3-yl-1,3,4-thiadiazol-2-yl)ethanamide | 2-(4-nitrophenoxy)-N-[5-(3-pyridinyl)-1,3,4-thiadiazol-2-yl]acetamide | 2-(4-nitrophenoxy)-N-[5-(3-pyridyl)-1,3,4-thiadiazol-2-yl]acetamide | MLS000767020 | SMR000385697 | cid_2320014
Type:
Small organic molecule
Emp. Form.:
C15H11N5O4S
Mol. Mass.:
357.344
SMILES:
[O-][N+](=O)c1ccc(OCC(=O)Nc2nnc(s2)-c2cccnc2)cc1
Structure:
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