Reaction Details Report a problem with these data
Target
High affinity choline transporter 1
Ligand
BDBM89165
Substrate
n/a
Meas. Tech.
Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC
EC50
13800±n/a nM
Citation
 PubChem, PC Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC PubChem Bioassay (2012)[AID] 
Target
Name:
High affinity choline transporter 1
Synonyms:
CHT1 | High-affinity choline transporter | SC5A7_HUMAN | SLC5A7 | high affinity choline transporter 1
Type:
PROTEIN
Mol. Mass.:
63194.33
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1464247
Residue:
580
Sequence:
MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGGLYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSWLDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDWNQTAYGLPDPKTTEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQLLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFKTLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLDELALVKPRQSMTLSSTFTNKEAFLDVDSSPEGSGTEDNLQ
  
Inhibitor
Name:
BDBM89165
Synonyms:
2-[2-({[1-(1-adamantyl)ethyl]amino}methyl)-4-bromophenoxy]acetamide hydrochloride | 2-[2-[[1-(1-adamantyl)ethylamino]methyl]-4-bromanyl-phenoxy]ethanamide;hydrochloride | 2-[2-[[1-(1-adamantyl)ethylamino]methyl]-4-bromo-phenoxy]acetamide;hydrochloride | 2-[2-[[1-(1-adamantyl)ethylamino]methyl]-4-bromophenoxy]acetamide;hydrochloride | MLS001000696 | SMR000498068 | cid_2962652
Type:
Small organic molecule
Emp. Form.:
C21H29BrN2O2
Mol. Mass.:
421.371
SMILES:
[H]C12CC3([H])CC([H])(C1)CC(C2)(C3)C(C)NCc1cc(Br)ccc1OCC(N)=O |TLB:8:6:12:1.11.2,5:3:11:6.9.8,THB:5:6:11:3.12.2|
Structure:
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