Reaction Details Report a problem with these data
Target
High affinity choline transporter 1
Ligand
BDBM89170
Substrate
n/a
Meas. Tech.
Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC
EC50
15500±n/a nM
Citation
 PubChem, PC Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC PubChem Bioassay (2012)[AID] 
Target
Name:
High affinity choline transporter 1
Synonyms:
CHT1 | High-affinity choline transporter | SC5A7_HUMAN | SLC5A7 | high affinity choline transporter 1
Type:
PROTEIN
Mol. Mass.:
63194.33
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1464247
Residue:
580
Sequence:
MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGGLYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSWLDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDWNQTAYGLPDPKTTEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQLLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFKTLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLDELALVKPRQSMTLSSTFTNKEAFLDVDSSPEGSGTEDNLQ
  
Inhibitor
Name:
BDBM89170
Synonyms:
(2-methoxy-5-methyl-phenyl)-[5-[4-(methylthio)phenyl]-4-phenyl-1,3,4-thiadiazol-4-ium-2-yl]amine;chloride | MLS000948481 | N-(2-methoxy-5-methyl-phenyl)-5-(4-methylsulfanylphenyl)-4-phenyl-1,3,4-thiadiazol-4-ium-2-amine;chloride | N-(2-methoxy-5-methylphenyl)-5-(4-methylsulfanylphenyl)-4-phenyl-1,3,4-thiadiazol-4-ium-2-amine;chloride | N-(2-methoxy-5-methylphenyl)-5-[4-(methylthio)phenyl]-4-phenyl-1,3,4-thiadiazol-4-ium-2-amine;chloride | SMR000526897 | cid_24789724
Type:
Small organic molecule
Emp. Form.:
C23H22N3OS2
Mol. Mass.:
420.57
SMILES:
COc1ccc(C)cc1Nc1n[n+](c(s1)-c1ccc(SC)cc1)-c1ccccc1
Structure:
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