Reaction Details Report a problem with these data
Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM89045
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen.
IC50
5570±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen. PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM89045
Synonyms:
3,4-diethoxybenzoic acid [(Z)-[amino-(4-methoxyphenyl)methylene]amino] ester | 3,4-diethoxybenzoic acid [(Z)-[amino-(4-methoxyphenyl)methylidene]amino] ester | MLS-0454715.0001 | [(Z)-[amino-(4-methoxyphenyl)methylidene]amino] 3,4-diethoxybenzoate | [(Z)-[azanyl-(4-methoxyphenyl)methylidene]amino] 3,4-diethoxybenzoate | cid_9587668
Type:
Small organic molecule
Emp. Form.:
C19H22N2O5
Mol. Mass.:
358.3884
SMILES:
CCOc1ccc(cc1OCC)C(=O)ON=C(N)c1ccc(OC)cc1 |w:15.15|
Structure:
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