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Target
Beta-2 adrenergic receptor
Ligand
BDBM84219
Substrate
n/a
Meas. Tech.
Dose response for HTS for Beta-2AR agonists via FAP method from Powderset3
EC50
1.53±n/a nM
Citation
 PubChem, PC Dose response for HTS for Beta-2AR agonists via FAP method from Powderset3 PubChem Bioassay (2012)[AID] 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM84219
Synonyms:
MLS000538561 | N-[2-(4-allyl-5-{[2-(4-chlorophenyl)-2-oxoethyl]thio}-4H-1,2,4-triazol-3-yl)ethyl]-2-thiophenecarboxamide | N-[2-[4-allyl-5-[[2-(4-chlorophenyl)-2-keto-ethyl]thio]-1,2,4-triazol-3-yl]ethyl]thiophene-2-carboxamide | N-[2-[5-[2-(4-chlorophenyl)-2-oxidanylidene-ethyl]sulfanyl-4-prop-2-enyl-1,2,4-triazol-3-yl]ethyl]thiophene-2-carboxamide | N-[2-[5-[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl-4-prop-2-enyl-1,2,4-triazol-3-yl]ethyl]thiophene-2-carboxamide | N-[2-[5-[[2-(4-chlorophenyl)-2-oxoethyl]thio]-4-prop-2-enyl-1,2,4-triazol-3-yl]ethyl]-2-thiophenecarboxamide | SMR000144598 | cid_2233849
Type:
Small organic molecule
Emp. Form.:
C20H19ClN4O2S2
Mol. Mass.:
446.973
SMILES:
Clc1ccc(cc1)C(=O)CSc1nnc(CCNC(=O)c2cccs2)n1CC=C
Structure:
Search PDB for entries with ligand similarity: