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Target
Beta-2 adrenergic receptor
Ligand
BDBM77324
Substrate
n/a
Meas. Tech.
Dose response for HTS for Beta-2AR agonists via FAP method from Powderset3
EC50
60.9±n/a nM
Citation
 PubChem, PC Dose response for HTS for Beta-2AR agonists via FAP method from Powderset3 PubChem Bioassay (2012)[AID] 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor
Type:
n/a
Mol. Mass.:
46461.69
Organism:
Homo sapiens (Human)
Description:
P07550
Residue:
413
Sequence:
MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNTGEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
  
Inhibitor
Name:
BDBM77324
Synonyms:
MLS000531823 | N-benzyl-4-(benzylsulfonylamino)-N-methyl-benzenesulfonamide | N-benzyl-4-(benzylsulfonylamino)-N-methylbenzenesulfonamide | N-benzyl-4-[(benzylsulfonyl)amino]-N-methylbenzenesulfonamide | N-methyl-N-(phenylmethyl)-4-[(phenylmethyl)sulfonylamino]benzenesulfonamide | SMR000136801 | cid_1025603
Type:
Small organic molecule
Emp. Form.:
C21H22N2O4S2
Mol. Mass.:
430.54
SMILES:
CN(Cc1ccccc1)S(=O)(=O)c1ccc(NS(=O)(=O)Cc2ccccc2)cc1
Structure:
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