Reaction Details Report a problem with these data
Target
Tyrosine-protein phosphatase non-receptor type 5
Ligand
BDBM88769
Substrate
n/a
Meas. Tech.
Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay.
IC50
27000±n/a nM
Citation
 PubChem, PC Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay. PubChem Bioassay (2012)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 5
Synonyms:
PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
63510.68
Organism:
Homo sapiens (Human)
Description:
gi_90652859
Residue:
565
Sequence:
MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPPPPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLVSSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQSPE
  
Inhibitor
Name:
BDBM88769
Synonyms:
4-[2-(dimethylamino)ethyl-[(4-phenoxyanilino)-sulfanylidenemethyl]amino]-1-piperidinecarboxylic acid ethyl ester | 4-[2-(dimethylamino)ethyl-[(4-phenoxyphenyl)thiocarbamoyl]amino]piperidine-1-carboxylic acid ethyl ester | MLS000689506 | SMR000311544 | cid_16195551 | ethyl 4-([2-(dimethylamino)ethyl]{[(4-phenoxyphenyl)amino]carbonothioyl}amino)piperidine-1-carboxylate | ethyl 4-[2-(dimethylamino)ethyl-[(4-phenoxyphenyl)carbamothioyl]amino]piperidine-1-carboxylate
Type:
Small organic molecule
Emp. Form.:
C25H34N4O3S
Mol. Mass.:
470.627
SMILES:
CCOC(=O)N1CCC(CC1)N(CCN(C)C)C(=S)Nc1ccc(Oc2ccccc2)cc1
Structure:
Search PDB for entries with ligand similarity: