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Target
Tyrosine-protein phosphatase non-receptor type 5
Ligand
BDBM83199
Substrate
n/a
Meas. Tech.
Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay.
IC50
>80000±n/a nM
Citation
 PubChem, PC Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay. PubChem Bioassay (2012)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 5
Synonyms:
PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
63510.68
Organism:
Homo sapiens (Human)
Description:
gi_90652859
Residue:
565
Sequence:
MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPPPPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLVSSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQSPE
  
Inhibitor
Name:
BDBM83199
Synonyms:
2-[7-(dihydroxymethylene)-5,6-diketo-cyclohepta-1,3-dien-1-yl]acetic acid | 2-[7-(dihydroxymethylidene)-5,6-dioxo-1-cyclohepta-1,3-dienyl]acetic acid | 2-[7-(dihydroxymethylidene)-5,6-dioxocyclohepta-1,3-dien-1-yl]acetic acid | 2-[7-[bis(oxidanyl)methylidene]-5,6-bis(oxidanylidene)cyclohepta-1,3-dien-1-yl]ethanoic acid | 7-(carboxymethyl)-2-hydroxy-3-keto-cyclohepta-1,4,6-triene-1-carboxylic acid | MLS002703575 | SMR001570292 | cid_5380595
Type:
Small organic molecule
Emp. Form.:
C10H8O6
Mol. Mass.:
224.1669
SMILES:
OC(=O)Cc1cccc(=O)c(O)c1C(O)=O
Structure:
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