Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM61664
Substrate
n/a
IC50
12984±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and receptor-interacting serine-threonine kinase 2 (RIPK2) PubChem Bioassay (2012)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM61664
Synonyms:
1-anilino-3-(4-chlorophenyl)-1H-pyrrole-2,5-dione | 1-anilino-3-(4-chlorophenyl)-3-pyrroline-2,5-quinone | 1-anilino-3-(4-chlorophenyl)pyrrole-2,5-dione | 3-(4-chlorophenyl)-1-phenylazanyl-pyrrole-2,5-dione | MLS000540412 | SMR000125670 | cid_1484340
Type:
Small organic molecule
Emp. Form.:
C16H11ClN2O2
Mol. Mass.:
298.724
SMILES:
Clc1ccc(cc1)C1=CC(=O)N(Nc2ccccc2)C1=O |t:8|
Structure:
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