Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM61540
Substrate
n/a
IC50
11345±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and receptor-interacting serine-threonine kinase 2 (RIPK2) PubChem Bioassay (2012)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM61540
Synonyms:
5-(4-chlorophenyl)sulfonyl-N-methyl-1,2,3-thiadiazole-4-carboxamide | 5-(4-chlorophenyl)sulfonyl-N-methyl-4-thiadiazolecarboxamide | 5-(4-chlorophenyl)sulfonyl-N-methyl-thiadiazole-4-carboxamide | 5-(4-chlorophenyl)sulfonyl-N-methylthiadiazole-4-carboxamide | 5-[(4-chlorophenyl)sulfonyl]-N-methyl-1,2,3-thiadiazole-4-carboxamide | MLS000707178 | SMR000334563 | cid_1487013
Type:
Small organic molecule
Emp. Form.:
C10H8ClN3O3S2
Mol. Mass.:
317.772
SMILES:
CNC(=O)c1nnsc1S(=O)(=O)c1ccc(Cl)cc1
Structure:
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