Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM80060
Substrate
n/a
IC50
19927±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and receptor-interacting serine-threonine kinase 2 (RIPK2) PubChem Bioassay (2012)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM80060
Synonyms:
2-(2-methyl-1H-indol-3-yl)-p-benzoquinone | 2-(2-methyl-1H-indol-3-yl)cyclohexa-2,5-diene-1,4-dione | MLS002608530 | SMR001527277 | cid_238781
Type:
Small organic molecule
Emp. Form.:
C15H11NO2
Mol. Mass.:
237.2533
SMILES:
Cc1[nH]c2ccccc2c1C1=CC(=O)C=CC1=O |c:16,t:12|
Structure:
Search PDB for entries with ligand similarity: